New class of antibodies protects against HIV-1 infection

Texas Biomedical Research Institute

A group of scientists at Texas Biomedical Research Institute have zeroed in on a new defense against HIV-1, the virus that causes AIDS. Led by Ruth Ruprecht, M.D., Ph.D., the team used an animal model to show for the first time that an antibody called Immunoglobulin M (IgM) was effective in preventing infection after mucosal AIDS virus exposure. Worldwide, an estimated 90% of new cases of HIV-1 are caused through exposure in the mucosal cavities like the inside lining of the rectum or vagina.

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Green tea ingredient may ameliorate memory impairment, brain insulin resistance, and obesity

Federation of American Societies for Experimental Biology A study published online in The FASEB Journal, involving mice, suggests that EGCG (epigallocatechin-3-gallate), the most abundant catechin and biologically active component in green tea, could alleviate high-fat and high-fructose (HFFD)-induced insulin resistance and cognitive impairment. Previous research pointed to the potential of EGCG to treat a variety of human diseases, yet until now, EGCG's impact on insulin resistance and cognitive deficits triggered in the brain by a Western diet remained unclear. Journal Reference: Yashi Mi, Guoyuan Qi, Rong Fan, Qinglian Qiao, Yali Sun, Yuqi Gao, Xuebo Liu. EGCG ameliorates high-fat– and high-fructose–induced cognitive defects by regulating the IRS/AKT and ERK/CREB/BDNF. The FASEB Journal, 2017; fj.201700400RR DOI: 10.1096/fj.201700400RR

HEALTH BENEFITS OF CHEWING RAW GARLIC

HEALTH BENEFITS OF CHEWING RAW GARLIC You might not make a lot of new friends if you chew on garlic, a plant used for centuries as both a pungent flavoring and a medicine. A member of the onion family, garlic contains a powerful sulfur compound called allicin, which also lends it a distinctive – and to many people, unpleasant – smell.Garlic not only makes food delicious, it may also have a number of health benefits. The allicin in garlic exhibits strong antioxidant activity – the ability to fight harmful free radicals in the body – which has led scientists to study its health-promoting properties. OFFERS AN ANTI-INFLAMMATORY EFFECT If you suffer from an inflammatory condition, it may help to consume raw garlic. A study published in "Food and Chemical Toxicology" in August 2013 found that garlic had an anti-inflammatory effect, with raw garlic exhibiting a stronger effect than garlic that had been heated. The levels of a compound called allicin were great

Using mushrooms as a prebiotic may help improve glucose regulation

August 16, 2018 Penn State Eating white button mushrooms can create subtle shifts in the microbial community in the gut, which could improve the regulation of glucose in the liver, according to a team of researchers. They also suggest that better understanding this connection between mushrooms and gut microbes in mice could one day pave the way for new diabetes treatments and prevention strategies for people.

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